MAP3K19

Across TCGA cell cohorts, MAP3K19 RNA expression is significantly associated with the go_rna of many other GO terms, with 887 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP3K19-associated GO terms across cancer lineages are Regulation of nucleocytoplasmic transport, Negative regulation of mRNA metabolic process, and Protein polyubiquitination. Each is linked with MAP3K19 in more than 7 cancer types. Because this analysis shows association rather than direction, both MAP3K19-to-partner and partner-to-MAP3K19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleocytoplasmic transport grouped by MAP3K19-low versus MAP3K19-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K19→partner) and Y-score (partner→MAP3K19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of nucleocytoplasmic transport →	+0.065	+0.045	.001	.007	2	8
STOMACH	Negative regulation of mRNA metabolic process →	+0.076	+0.037	.003	.009	3	5
STOMACH	Protein polyubiquitination →	+0.069	+0.071	<.001	.002	3	5
STOMACH	Protein localization to lysosome →	+0.087	+0.065	.002	.009	3	5
STOMACH	Protein modification by small protein removal →	+0.057	+0.050	<.001	.003	3	5
BONE	Cilium movement →	-0.075	-0.015	.005	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 887 associations by consensus.

Regulation of nucleocytoplasmic transport by MAP3K19 expression — STOMACH

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