MAP3K11

Across TCGA patient cohorts, MAP3K11 protein abundance is significantly associated with the RNA expression of many other genes, with 4,567 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAP3K11-associated genes across cancer lineages are FAM50B, SIGLEC14, and TNFRSF10C. Each is linked with MAP3K11 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP3K11-to-partner and partner-to-MAP3K11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K11 versus FAM50B in BRCA, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K11→partner) and Y-score (partner→MAP3K11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM50B →	+0.533	+0.201	.002	.001	3	3
GBM	SIGLEC14 →	+1.343	+0.284	<.001	<.001	3	3
LUAD	TNFRSF10C →	+0.867	+0.145	.002	.006	3	3
PDAC	POLR2C →	-0.347	-0.591	<.001	.001	3	2
PDAC	GPI →	-0.487	-0.519	.001	.009	3	2
OV	MRPS30 →	-0.395	-0.359	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,567 associations by consensus.

MAP3K11 vs FAM50B — BRCA

Explore this scatter interactively →