MAP3K1

Across TCGA patient cohorts, MAP3K1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,156 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MAP3K1-associated genes across cancer lineages are OR13F1, MEIS3P2, and GREB1. Each is linked with MAP3K1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP3K1-to-partner and partner-to-MAP3K1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K1 versus OR13F1 in CCRCC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K1→partner) and Y-score (partner→MAP3K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	OR13F1 →	+0.121	+0.208	.003	.009	3	2
BRCA	MEIS3P2 →	+0.839	+0.298	.001	<.001	3	2
BRCA	GREB1 →	+1.256	+0.270	<.001	<.001	3	2
CCRCC	RBM5-AS1 →	+0.265	+0.207	<.001	.002	3	2
CCRCC	EPHA6 →	-1.103	-0.282	.001	.001	3	2
UCEC	RNU4-22P →	-0.979	-0.206	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,156 associations by consensus.

MAP3K1 vs OR13F1 — CCRCC

Explore this scatter interactively →