MAP2K7

Across TCGA patient cohorts, MAP2K7 protein abundance is significantly associated with the RNA expression of many other genes, with 4,894 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAP2K7-associated genes across cancer lineages are XAB2, CCDC130, and TIMM44. Each is linked with MAP2K7 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAP2K7-to-partner and partner-to-MAP2K7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP2K7 versus XAB2 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP2K7→partner) and Y-score (partner→MAP2K7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XAB2 →	+0.604	+0.245	<.001	<.001	3	4
LSCC	CCDC130 →	+0.489	+0.232	<.001	<.001	3	3
OV	TIMM44 →	+0.753	+0.465	<.001	<.001	3	3
LSCC	YJU2 →	+0.475	+0.256	<.001	<.001	3	3
LSCC	GCDH →	+0.487	+0.206	.001	.001	3	3
LSCC	SUGP1 →	+0.397	+0.199	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,894 associations by consensus.

MAP2K7 vs XAB2 — LSCC

Explore this scatter interactively →