MAP2K5

Across TCGA cell cohorts, MAP2K5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,539 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAP2K5-associated GO terms across cancer lineages are Circadian sleep/wake cycle, Regulation of cell-cell adhesion involved in gastrulation, and Negative regulation of heterotypic cell-cell adhesion. Each is linked with MAP2K5 in more than 11 cancer types. Because this analysis shows association rather than direction, both MAP2K5-to-partner and partner-to-MAP2K5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Circadian sleep/wake cycle grouped by MAP2K5-low versus MAP2K5-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP2K5→partner) and Y-score (partner→MAP2K5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Circadian sleep/wake cycle →	+0.168	+1.056	<.001	<.001	3	12
BONE	Regulation of cell-cell adhesion involved in gastrulation →	+0.136	+0.928	.001	<.001	3	11
BONE	Negative regulation of heterotypic cell-cell adhesion →	+0.136	+0.928	.001	<.001	3	11
BLOOD_Lymphoma	Insulin-like growth factor receptor signaling pathway →	+0.095	+0.966	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Post-Golgi vesicle-mediated transport →	+0.051	+0.572	<.001	<.001	3	10
BONE	RNA import into nucleus →	+0.105	+1.046	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,539 associations by consensus.

Circadian sleep/wake cycle by MAP2K5 expression — OVARY

Explore this box plot interactively →