MAP2K1P1

Across TCGA patient cohorts, MAP2K1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,821 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP2K1P1-associated GO terms across cancer lineages are Positive regulation of protein ubiquitination, Positive regulation of mRNA 3'-end processing, and COPII-coated vesicle cargo loading. Each is linked with MAP2K1P1 in more than 23 cancer types. Because this analysis shows association rather than direction, both MAP2K1P1-to-partner and partner-to-MAP2K1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein ubiquitination grouped by MAP2K1P1-low versus MAP2K1P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP2K1P1→partner) and Y-score (partner→MAP2K1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of protein ubiquitination →	+0.038	+0.159	<.001	<.001	3	23
DLBC	Positive regulation of mRNA 3'-end processing →	+0.057	+0.099	.002	.007	2	24
DLBC	COPII-coated vesicle cargo loading →	+0.094	+0.193	.001	<.001	2	23
ESCA	Regulation of microtubule polymerization or depolymerization →	+0.042	+0.154	.003	.001	2	23
STAD	Regulation of protein ubiquitination →	+0.036	+0.122	<.001	<.001	3	22
DLBC	Positive regulation of proteasomal protein catabolic process →	+0.050	+0.210	.006	<.001	2	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,821 associations by consensus.

Positive regulation of protein ubiquitination by MAP2K1P1 expression — STAD

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