MAP2

Across TCGA cell cohorts, MAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,116 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MAP2-associated GO terms across cancer lineages are Regulation of vesicle transport along microtubule, Positive regulation of vesicle transport along microtubule, and Phospholipase C-activating G protein-coupled receptor signaling pathway. Each is linked with MAP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both MAP2-to-partner and partner-to-MAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vesicle transport along microtubule grouped by MAP2-low versus MAP2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP2→partner) and Y-score (partner→MAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of vesicle transport along microtubule →	+0.297	+2.872	.003	<.001	2	11
LUNG_NSCLC_LUAD	Positive regulation of vesicle transport along microtubule →	+0.297	+2.872	.003	<.001	2	11
OVARY	Phospholipase C-activating G protein-coupled receptor signaling pathway →	-0.059	-2.025	<.001	<.001	3	9
STOMACH	Negative regulation of myoblast fusion →	+0.162	+2.191	<.001	.004	3	9
STOMACH	Transcription initiation at RNA polymerase II promoter →	+0.046	+1.771	.006	.006	3	8
OVARY	Regulation of cytoplasmic translation →	+0.110	+2.559	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,116 associations by consensus.

Regulation of vesicle transport along microtubule by MAP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →