MAP2

Across TCGA cell cohorts, MAP2 mutation is significantly associated with the RNA expression of many other genes, with 521 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAP2-associated genes across cancer lineages are GALNTL5, IFNA17, and USP17L17. Each is linked with MAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP2-to-partner and partner-to-MAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALNTL5 grouped by MAP2-low versus MAP2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP2→partner) and Y-score (partner→MAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GALNTL5 →	+0.037	+4.087	<.001	.009	3	2
OVARY	IFNA17 →	+0.010	+3.807	<.001	.009	3	2
OVARY	USP17L17 →	+0.006	+3.807	<.001	.009	3	2
LARGE_INTESTINE	PCCB →	+0.433	+1.544	.003	.008	3	2
LARGE_INTESTINE	SLC25A38 →	+0.386	+1.894	.002	.001	3	2
LARGE_INTESTINE	DLAT →	+0.448	+1.630	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 521 associations by consensus.

GALNTL5 by MAP2 expression — URINARY_TRACT

Explore this box plot interactively →