MAP1LC3P

Across TCGA pan-cancer cohorts, MAP1LC3P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MAP1LC3P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MAP1LC3P RNA is repressed in tumor relative to normal tissue. In most cancer types MAP1LC3P is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.

COAD, LUSC, and KICH are the cancer types where MAP1LC3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAP1LC3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	−0.115	.002	4	view →
LUSC	All	All	−0.063	.004	4	view →
KICH	All	All	+0.103	.003	3	view →
STAD	All	II,III,IV	+0.134	.037	2	view →
KIRC	Male	II,III,IV	+0.028	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MAP1LC3P–COAD

Open the COAD breakdown →