MAP1LC3B2

Across TCGA patient cohorts, MAP1LC3B2 mutation is significantly associated with the RNA expression of many other genes, with 352 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP1LC3B2-associated genes across cancer lineages are RN7SL97P, OSTF1P1, and OR4M1. Each is linked with MAP1LC3B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP1LC3B2-to-partner and partner-to-MAP1LC3B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL97P grouped by MAP1LC3B2-low versus MAP1LC3B2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1LC3B2→partner) and Y-score (partner→MAP1LC3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL97P →	+0.211	+6.144	<.001	.001	3	2
UCEC	OSTF1P1 →	+0.279	+2.138	<.001	.007	3	2
SKCM	OR4M1 →	+0.036	+4.513	<.001	.009	3	1
SKCM	OR4C15 →	+0.053	+5.328	<.001	.003	3	1
SKCM	RNA5SP339 →	+0.269	+4.970	<.001	.005	3	1
SKCM	RNU6-192P →	+0.430	+6.219	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 352 associations by consensus.

RN7SL97P by MAP1LC3B2 expression — CESC

Explore this box plot interactively →