MAP1LC3B2

Across TCGA cell cohorts, MAP1LC3B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,112 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MAP1LC3B2-associated GO terms across cancer lineages are Regulation of macroautophagy, Negative regulation of macroautophagy, and Positive regulation of TORC1 signaling. Each is linked with MAP1LC3B2 in more than 9 cancer types. Because this analysis shows association rather than direction, both MAP1LC3B2-to-partner and partner-to-MAP1LC3B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by MAP1LC3B2-low versus MAP1LC3B2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1LC3B2→partner) and Y-score (partner→MAP1LC3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.073	+0.969	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of macroautophagy →	+0.079	+0.849	<.001	.001	3	9
STOMACH	Positive regulation of TORC1 signaling →	+0.102	+0.933	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Response to dehydroepiandrosterone →	+0.166	+0.771	<.001	<.001	3	9
BLOOD_Leukemia	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.055	+0.571	.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.087	+0.969	.004	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,112 associations by consensus.

Regulation of macroautophagy by MAP1LC3B2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →