MAP1B

Across TCGA cell cohorts, MAP1B mutation is significantly associated with the RNA expression of many other genes, with 897 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAP1B-associated genes across cancer lineages are OR8B4, PATE3, and CFHR2. Each is linked with MAP1B in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP1B-to-partner and partner-to-MAP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B4 grouped by MAP1B-low versus MAP1B-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1B→partner) and Y-score (partner→MAP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR8B4 →	+0.036	+4.906	<.001	.006	3	2
LIVER	PATE3 →	+0.024	+3.459	<.001	.004	3	2
BONE	CFHR2 →	+0.045	+4.169	<.001	.008	3	2
STOMACH	MIER1 →	+0.661	+3.070	.003	.008	3	2
SKIN	TRIM62 →	+0.943	+3.364	.001	.002	3	2
BLOOD_Leukemia	GABPB2 →	+0.754	+3.321	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 897 associations by consensus.

OR8B4 by MAP1B expression — OESOPHAGUS

Explore this box plot interactively →