MAP11

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MAP11 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MAP11 data layer compared with 23 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MAP11 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MAP11 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

COAD and UCEC are the cancer types where MAP11 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSMedianIII,IV0.2210.782.0139view →
UCECDFSMedianAll0.9680.829.0334view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

MAP11–COAD (OS)

Kaplan–Meier survival curve for MAP11 mutant vs wild-type samples in COAD.

Open the COAD breakdown →

Exploration