MAP11

Across TCGA patient cohorts, MAP11 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP11-associated genes across cancer lineages are Caspase-7-cleavedD198, Rictor_pT1135, and ATM. Each is linked with MAP11 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP11-to-partner and partner-to-MAP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by MAP11-low versus MAP11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP11→partner) and Y-score (partner→MAP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.721	+1.894	.001	.030	3	3
UCEC	Rictor_pT1135 →	-0.088	-2.502	.028	.002	3	2
UCEC	ATM →	-0.404	-1.584	.023	.036	3	2
UCEC	EGFR →	-0.135	-2.000	.032	.010	3	1
UCEC	ERK2 →	+0.167	+2.115	.027	.017	3	1
UCEC	JNK_pT183_Y185 →	-0.142	-1.571	.032	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Caspase-7-cleavedD198 by MAP11 expression — UCEC

Explore this box plot interactively →