MAP11

Across TCGA cell cohorts, MAP11 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MAP11-associated genes across cancer lineages are DMRTC2, OR52R1, and ASB17. Each is linked with MAP11 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP11-to-partner and partner-to-MAP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMRTC2 grouped by MAP11-low versus MAP11-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP11→partner) and Y-score (partner→MAP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DMRTC2 →	+0.007	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	OR52R1 →	+0.037	+4.058	<.001	.009	3	1
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
BLOOD_Leukemia	DPRX →	+0.117	+5.060	<.001	.001	3	1
LARGE_INTESTINE	TMCO5A →	+0.026	+5.415	<.001	.004	3	1
BLOOD_Lymphoma	ECE2 →	+0.048	+3.736	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

DMRTC2 by MAP11 expression — BLOOD_Lymphoma

Explore this box plot interactively →