Across TCGA cell cohorts, MAOA mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAOA-associated genes across cancer lineages are CCDC140, GUCA2B, and WDR87. Each is linked with MAOA in more than 1 cancer types. Because this analysis shows association rather than direction, both MAOA-to-partner and partner-to-MAOA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAOA→partner) and Y-score (partner→MAOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CCDC140 →	+0.212	+4.705	<.001	.003	3	1
BLOOD_Leukemia	GUCA2B →	+0.032	+4.969	<.001	.003	3	1
LARGE_INTESTINE	WDR87 →	+0.023	+3.453	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

MAOA survival (RNA) · tumor vs normal (RNA) · all MAOA data types