Across TCGA patient cohorts, MANSC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,048 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MANSC4-associated proteins across cancer lineages are MEN1, MACIR_S25, and PHF10. Each is linked with MANSC4 in more than 3 cancer types. Because this analysis shows association rather than direction, both MANSC4-to-partner and partner-to-MANSC4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MANSC4→partner) and Y-score (partner→MANSC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MEN1 →	+0.302	+0.614	<.001	.001	3	4
HNSC	MACIR_S25 →	+0.703	+0.604	<.001	.009	3	3
LSCC	PHF10 →	+0.299	+0.378	<.001	.004	3	3
GBM	TLE3_S203 →	+0.653	+0.428	<.001	<.001	3	3
GBM	POGZ →	+0.333	+0.433	<.001	<.001	3	3
HNSC	PSIP1 →	+0.541	+0.372	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,048 associations by consensus.

Exploration

MANSC4 survival (RNA) · tumor vs normal (RNA) · all MANSC4 data types