MANSC1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MANSC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,899 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MANSC1-associated GO terms across cancer lineages are Golgi to endosome transport, Sensory perception of salty taste, and Membrane bending. Each is linked with MANSC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MANSC1-to-partner and partner-to-MANSC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi to endosome transport grouped by MANSC1-low versus MANSC1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MANSC1→partner) and Y-score (partner→MANSC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHGolgi to endosome transport →+0.111+1.924.003.004310
LUNG_SCLCSensory perception of salty taste →+1.236+1.647<.001<.001310
LARGE_INTESTINEMembrane bending →+0.170+1.662<.001.00139
LUNG_SCLCHexose phosphate transport →+0.473+1.908.003<.00139
LUNG_SCLCGlucose-6-phosphate transport →+0.473+1.908.003<.00139
CNSIntracellular pH reduction →+0.077+1.604<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,899 associations by consensus.

Golgi to endosome transport by MANSC1 expression — STOMACH

Box plot of Golgi to endosome transport in MANSC1-low vs MANSC1-high samples in STOMACH.

Explore this box plot interactively →

Exploration