Across TCGA cell cohorts, MANEAL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,663 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MANEAL-associated GO terms across cancer lineages are Nucleosome disassembly, RISC complex assembly, and DNA strand elongation involved in DNA replication. Each is linked with MANEAL in more than 8 cancer types. Because this analysis shows association rather than direction, both MANEAL-to-partner and partner-to-MANEAL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MANEAL→partner) and Y-score (partner→MANEAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nucleosome disassembly →	+0.098	+1.467	.007	.006	2	9
BLOOD_Lymphoma	RISC complex assembly →	+0.076	+0.826	<.001	<.001	3	8
BREAST	DNA strand elongation involved in DNA replication →	+0.115	+1.127	.001	.009	2	8
BLOOD_Lymphoma	Heterochromatin formation →	+0.049	+0.873	.002	.002	3	7
BREAST	Constitutive heterochromatin formation →	+0.078	+1.367	<.001	.009	3	6
BREAST	Positive regulation of potassium ion transmembrane transport →	-0.172	-1.508	.003	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,663 associations by consensus.

Exploration

MANEAL survival (RNA) · tumor vs normal (RNA) · all MANEAL data types