MANBAL

Across TCGA cell cohorts, MANBAL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,224 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MANBAL-associated GO terms across cancer lineages are Intestinal epithelial cell development, Response to unfolded protein, and Mitotic centrosome separation. Each is linked with MANBAL in more than 11 cancer types. Because this analysis shows association rather than direction, both MANBAL-to-partner and partner-to-MANBAL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intestinal epithelial cell development grouped by MANBAL-low versus MANBAL-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MANBAL→partner) and Y-score (partner→MANBAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Intestinal epithelial cell development →	+1.038	+0.748	<.001	<.001	3	12
STOMACH	Response to unfolded protein →	+0.104	+0.917	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Mitotic centrosome separation →	+0.157	+0.960	.001	<.001	3	11
LIVER	Modification of synaptic structure →	+0.102	+0.498	.002	.001	2	11
STOMACH	IRE1-mediated unfolded protein response →	+0.144	+0.692	<.001	<.001	3	10
BLOOD_Lymphoma	Columnar/cuboidal epithelial cell development →	+1.098	+0.667	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,224 associations by consensus.

Intestinal epithelial cell development by MANBAL expression — BLOOD_Lymphoma

Explore this box plot interactively →