MAN2C1

Across TCGA patient cohorts, MAN2C1 mutation is significantly associated with the RNA expression of many other genes, with 1,939 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAN2C1-associated genes across cancer lineages are MIR6760, C1QBP, and CENPM. Each is linked with MAN2C1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAN2C1-to-partner and partner-to-MAN2C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6760 grouped by MAN2C1-low versus MAN2C1-high in KIRC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2C1→partner) and Y-score (partner→MAN2C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	MIR6760 →	+0.483	+7.203	<.001	<.001	3	3
COAD	C1QBP →	+0.632	+3.335	.004	.005	3	3
UCEC	CENPM →	+0.495	+1.836	.003	.001	3	3
UCEC	VPS18 →	+0.457	+2.431	<.001	.001	3	3
UCEC	ZWINT →	+0.636	+3.700	<.001	.001	3	3
UCEC	MED18 →	+0.426	+1.857	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,939 associations by consensus.

MIR6760 by MAN2C1 expression — KIRC

Explore this box plot interactively →