MAN2C1

Across TCGA cell cohorts, MAN2C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,844 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MAN2C1-associated GO terms across cancer lineages are mRNA splice site recognition, DNA replication proofreading, and Cilium or flagellum-dependent cell motility. Each is linked with MAN2C1 in more than 15 cancer types. Because this analysis shows association rather than direction, both MAN2C1-to-partner and partner-to-MAN2C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by MAN2C1-low versus MAN2C1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2C1→partner) and Y-score (partner→MAN2C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	mRNA splice site recognition →	+0.193	+1.804	<.001	<.001	3	16
BONE	DNA replication proofreading →	+0.172	+1.088	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.106	-1.264	<.001	<.001	3	15
BONE	Late viral transcription →	+0.138	+1.021	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.106	-1.264	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.109	-1.264	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,844 associations by consensus.

mRNA splice site recognition by MAN2C1 expression — OESOPHAGUS

Explore this box plot interactively →