Across TCGA patient cohorts, MAN2A2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,380 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAN2A2-associated genes across cancer lineages are SRSF9, UNC45A, and UCHL1. Each is linked with MAN2A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAN2A2-to-partner and partner-to-MAN2A2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2A2→partner) and Y-score (partner→MAN2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRSF9 →	+0.413	+0.249	.001	.006	3	3
LSCC	UNC45A →	+0.465	+0.264	<.001	<.001	3	3
LSCC	UCHL1 →	+2.448	+0.350	<.001	<.001	3	3
LSCC	KRT18P59 →	+0.365	+0.248	.008	.005	3	3
LSCC	MLLT11 →	+1.341	+0.363	<.001	<.001	3	3
HNSC	RARRES1 →	+1.349	+0.386	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,380 associations by consensus.

Exploration

MAN2A2 survival (RNA) · tumor vs normal (RNA) · all MAN2A2 data types