Across TCGA patient cohorts, MAN2A2 mutation is significantly associated with the RNA expression of many other genes, with 3,353 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAN2A2-associated genes across cancer lineages are PHF5A, MIR615, and SRA1. Each is linked with MAN2A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAN2A2-to-partner and partner-to-MAN2A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2A2→partner) and Y-score (partner→MAN2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PHF5A →	+0.466	+2.146	<.001	<.001	3	3
UCEC	MIR615 →	+0.199	+2.029	<.001	<.001	3	3
UCEC	SRA1 →	+0.297	+1.709	<.001	<.001	3	3
SKCM	RNU6-822P →	+0.120	+2.132	.003	.009	3	3
LIHC	MIR887 →	+0.254	+4.293	<.001	.009	3	2
UCEC	PSAT1P4 →	+0.133	+1.868	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,353 associations by consensus.

Exploration

MAN2A2 survival (RNA) · tumor vs normal (RNA) · all MAN2A2 data types