MAMLD1

Across TCGA patient cohorts, MAMLD1 protein abundance is significantly associated with the RNA expression of many other genes, with 742 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAMLD1-associated genes across cancer lineages are SNORD114-31, SNORD114-20, and RNU6-1035P. Each is linked with MAMLD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAMLD1-to-partner and partner-to-MAMLD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAMLD1 versus SNORD114-31 in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAMLD1→partner) and Y-score (partner→MAMLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD114-31 →	+1.815	+0.493	.004	<.001	3	1
UCEC	SNORD114-20 →	+1.594	+0.450	.006	.002	3	1
UCEC	RNU6-1035P →	-1.041	-0.443	.001	.008	3	1
UCEC	MIR551A →	-0.686	-0.680	.009	<.001	3	1
UCEC	HSPE1P6 →	-0.488	-0.407	.008	.003	3	1
UCEC	SUMO2P10 →	-1.022	-0.462	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

MAMLD1 vs SNORD114-31 — UCEC

Explore this scatter interactively →