MAMLD1

Across TCGA cell cohorts, MAMLD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,574 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAMLD1-associated GO terms across cancer lineages are Positive regulation of extracellular matrix organization, Positive regulation of focal adhesion assembly, and Regulation of plasminogen activation. Each is linked with MAMLD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both MAMLD1-to-partner and partner-to-MAMLD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of extracellular matrix organization grouped by MAMLD1-low versus MAMLD1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAMLD1→partner) and Y-score (partner→MAMLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of extracellular matrix organization →	+0.197	+2.179	<.001	<.001	3	13
BONE	Positive regulation of focal adhesion assembly →	+0.214	+2.184	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of plasminogen activation →	+0.375	+2.567	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Hypothalamus cell differentiation →	+0.351	+2.389	<.001	<.001	3	11
LUNG_SCLC	Tooth mineralization →	+0.365	+0.888	.007	.009	3	11
BONE	Neuropilin signaling pathway →	+0.278	+2.678	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,574 associations by consensus.

Positive regulation of extracellular matrix organization by MAMLD1 expression — LIVER

Explore this box plot interactively →