Across TCGA patient cohorts, MAML2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,828 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAML2-associated genes across cancer lineages are FAM83D, CDC20, and CDCA8. Each is linked with MAML2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAML2-to-partner and partner-to-MAML2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAML2→partner) and Y-score (partner→MAML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAM83D →	-1.123	-0.347	.001	.007	3	4
OV	CDC20 →	-0.929	-0.227	.001	.006	3	4
OV	CDCA8 →	-0.987	-0.282	<.001	<.001	3	4
GBM	PI4K2A →	-0.430	-0.269	<.001	.005	3	4
UCEC	S100A6 →	+1.228	+0.197	.001	.003	3	4
BRCA	JRKL →	+1.002	+0.400	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,828 associations by consensus.

Exploration

MAML2 survival (RNA) · tumor vs normal (RNA) · all MAML2 data types