Across TCGA cell cohorts, MAML2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,940 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAML2-associated GO terms across cancer lineages are Regulation of stress-activated protein kinase signaling cascade, Regulation of transforming growth factor beta receptor signaling pathway, and Positive regulation of stress-activated protein kinase signaling cascade. Each is linked with MAML2 in more than 13 cancer types. Because this analysis shows association rather than direction, both MAML2-to-partner and partner-to-MAML2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAML2→partner) and Y-score (partner→MAML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of stress-activated protein kinase signaling cascade →	+0.096	+1.445	<.001	<.001	3	14
BONE	Regulation of transforming growth factor beta receptor signaling pathway →	+0.066	+1.474	.001	.002	3	13
BONE	Positive regulation of stress-activated protein kinase signaling cascade →	+0.165	+1.317	<.001	<.001	3	12
BONE	Regulation of transforming growth factor beta production →	+0.162	+1.366	<.001	.005	3	12
BONE	Coagulation →	+0.124	+1.526	<.001	<.001	3	11
BONE	Platelet-derived growth factor receptor signaling pathway →	+0.102	+1.336	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,940 associations by consensus.

Exploration

MAML2 survival (RNA) · tumor vs normal (RNA) · all MAML2 data types