Across TCGA cell cohorts, MAML2 mutation is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAML2-associated genes across cancer lineages are GAL3ST2, TGM7, and SSX7. Each is linked with MAML2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAML2-to-partner and partner-to-MAML2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAML2→partner) and Y-score (partner→MAML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GAL3ST2 →	+1.294	+2.043	<.001	.008	3	2
SOFT_TISSUE	TGM7 →	+0.006	+5.369	<.001	.004	3	1
SOFT_TISSUE	SSX7 →	+0.019	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR10J3 →	+0.026	+5.369	<.001	.004	3	1
SOFT_TISSUE	MDFIC2 →	+0.266	+4.930	<.001	.008	3	1
CNS	FHL5 →	+0.015	+3.459	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

Exploration

MAML2 survival (RNA) · tumor vs normal (RNA) · all MAML2 data types