MAML1

Across TCGA patient cohorts, MAML1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,799 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MAML1-associated genes across cancer lineages are ZNF354C, DIO3OS, and NUAK1. Each is linked with MAML1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAML1-to-partner and partner-to-MAML1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAML1 versus ZNF354C in CCRCC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAML1→partner) and Y-score (partner→MAML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ZNF354C →	+0.867	+0.297	.005	.003	3	3
BRCA	DIO3OS →	+0.510	+0.427	.008	<.001	3	3
CCRCC	NUAK1 →	+0.648	+0.205	.006	.009	3	3
OV	THEM6 →	-0.875	-0.302	.001	.002	3	2
CCRCC	CDR2 →	-0.543	-0.320	.005	<.001	3	2
BRCA	RNA5SP498 →	+0.717	+0.340	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,799 associations by consensus.

MAML1 vs ZNF354C — CCRCC

Explore this scatter interactively →