MAMDC4

Across TCGA cell cohorts, MAMDC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,775 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MAMDC4-associated GO terms across cancer lineages are Microtubule nucleation, Calcium-independent cell-matrix adhesion, and Cilium-dependent cell motility. Each is linked with MAMDC4 in more than 13 cancer types. Because this analysis shows association rather than direction, both MAMDC4-to-partner and partner-to-MAMDC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by MAMDC4-low versus MAMDC4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAMDC4→partner) and Y-score (partner→MAMDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule nucleation →	+0.150	+1.347	<.001	<.001	3	14
URINARY_TRACT	Calcium-independent cell-matrix adhesion →	+0.208	+1.205	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.137	-1.246	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Late viral transcription →	+0.138	+0.852	<.001	.001	3	13
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.148	+1.124	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.137	-1.246	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,775 associations by consensus.

Microtubule nucleation by MAMDC4 expression — BONE

Explore this box plot interactively →