MAMDC2

Across TCGA patient cohorts, MAMDC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,097 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAMDC2-associated proteins across cancer lineages are KANK2, TLN1, and TNS1. Each is linked with MAMDC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both MAMDC2-to-partner and partner-to-MAMDC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAMDC2 versus KANK2 in UCEC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAMDC2→partner) and Y-score (partner→MAMDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KANK2 →	+0.686	+1.296	<.001	<.001	3	9
UCEC	TLN1 →	+0.417	+1.001	<.001	<.001	3	8
UCEC	TNS1 →	+0.691	+1.165	<.001	<.001	3	8
UCEC	TNS2_S648 →	+0.779	+1.576	<.001	<.001	3	8
COAD	TPM1 →	+0.880	+0.914	<.001	<.001	3	8
COAD	TPM2 →	+1.169	+0.926	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,097 associations by consensus.

MAMDC2 vs KANK2 — UCEC

Explore this scatter interactively →