MALT1

Across TCGA patient cohorts, MALT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,716 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MALT1-associated proteins across cancer lineages are SMAD4, SUCLG2, and TXNL1. Each is linked with MALT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MALT1-to-partner and partner-to-MALT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MALT1 versus SMAD4 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MALT1→partner) and Y-score (partner→MALT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SMAD4 →	+0.317	+0.556	<.001	<.001	3	6
OV	SUCLG2 →	-0.712	-0.891	<.001	<.001	3	5
OV	TXNL1 →	+0.311	+0.620	<.001	.007	3	5
BRCA	VPS4B →	+0.282	+0.689	<.001	<.001	3	5
OV	PDHX →	-0.460	-0.947	<.001	<.001	3	5
BRCA	SMAD2 →	+0.382	+0.597	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,716 associations by consensus.

MALT1 vs SMAD4 — COAD

Explore this scatter interactively →