MALINC1

Across TCGA pan-cancer cohorts, MALINC1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MALINC1 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher MALINC1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MALINC1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and KIRC show a favorable association.

CHOL, KIRC, and UVM are the cancer types where MALINC1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	II,III,IV	0.710	0.117	.001	41	view →
KIRC	DFS	Quartile	All	0.879	0.674	.002	41	view →
UVM	DFS	Tertile	III,IV	0.231	0.866	<.001	37	view →
SKCM	DFS	Quartile	All	0.275	0.148	.003	35	view →
LGG	OS	Median	All	0.950	0.838	<.001	33	view →
MESO	DFS	Quartile	All	0.172	0.682	.006	21	view →
ESCA	DFS	Tertile	IV	0.143	0.704	.024	18	view →
READ	OS	Tertile	III,IV	1.000	0.295	.003	14	view →
COAD	DFS	Quartile	All	0.359	0.665	.004	14	view →
KICH	DFS	Median	II,III,IV	0.606	0.915	.014	11	view →
BLCA	OS	Quartile	All	0.755	0.638	.019	11	view →
HNSC	OS	Quartile	III,IV	0.414	0.732	.016	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MALINC1–CHOL (DFS)

Open the CHOL breakdown →