MAL

Across TCGA patient cohorts, MAL RNA expression is significantly associated with the protein abundance of many other proteins, with 20,120 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAL-associated proteins across cancer lineages are ELMO1, LHPP, and S100A1. Each is linked with MAL in more than 4 cancer types. Because this analysis shows association rather than direction, both MAL-to-partner and partner-to-MAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAL versus ELMO1 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAL→partner) and Y-score (partner→MAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ELMO1 →	+0.633	+1.879	<.001	<.001	3	5
GBM	LHPP →	+0.524	+1.851	<.001	.001	3	5
UCEC	S100A1 →	+2.097	+2.144	<.001	<.001	3	5
UCEC	SEPTIN6_S388 →	+0.683	+1.551	<.001	.004	3	5
BRCA	ZAP70 →	+0.789	+0.658	<.001	<.001	3	5
PDAC	CLIC2 →	+0.469	+0.649	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,120 associations by consensus.

MAL vs ELMO1 — GBM

Explore this scatter interactively →