Across TCGA patient cohorts, MAK16 RNA expression is significantly associated with the RNA expression of many other genes, with 19,579 significant associations in total. ACC shows the largest number of these associations.

The most reproducible MAK16-associated genes across cancer lineages are CNOT7, PPP2R2A, and TRIM35. Each is linked with MAK16 in more than 33 cancer types. Because this analysis shows association rather than direction, both MAK16-to-partner and partner-to-MAK16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAK16→partner) and Y-score (partner→MAK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	CNOT7 →	+1.531	+0.669	<.001	<.001	3	34
ACC	PPP2R2A →	+1.178	+0.949	<.001	<.001	3	34
KICH	TRIM35 →	+0.999	+1.072	<.001	<.001	3	34
SKCM	ERI1 →	+0.974	+1.196	<.001	<.001	3	34
SKCM	MTMR9 →	+0.998	+1.198	<.001	<.001	3	34
ACC	DCTN6 →	+0.994	+0.740	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,579 associations by consensus.

Exploration

MAK16 survival (RNA) · tumor vs normal (RNA) · all MAK16 data types