Across TCGA cell cohorts, MAK16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,718 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAK16-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, Maturation of LSU-rRNA, and DNA-templated transcription initiation. Each is linked with MAK16 in more than 17 cancer types. Because this analysis shows association rather than direction, both MAK16-to-partner and partner-to-MAK16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAK16→partner) and Y-score (partner→MAK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	'de novo' IMP biosynthetic process →	+0.172	+1.197	<.001	<.001	3	18
BONE	Maturation of LSU-rRNA →	+0.199	+1.253	<.001	<.001	3	17
BONE	DNA-templated transcription initiation →	+0.084	+0.928	<.001	<.001	3	17
LIVER	RNA polymerase II transcription initiation surveillance →	+0.118	+1.337	<.001	<.001	3	16
BONE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.110	+0.697	<.001	.003	3	16
BONE	rRNA processing →	+0.147	+1.012	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,718 associations by consensus.

Exploration

MAK16 survival (RNA) · tumor vs normal (RNA) · all MAK16 data types