MAJIN

Across TCGA patient cohorts, MAJIN RNA expression is significantly associated with the go_rna of many other GO terms, with 7,089 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MAJIN-associated GO terms across cancer lineages are Meiotic attachment of telomere to nuclear envelope, Telomere tethering at nuclear periphery, and Chromosome attachment to the nuclear envelope. Each is linked with MAJIN in more than 24 cancer types. Because this analysis shows association rather than direction, both MAJIN-to-partner and partner-to-MAJIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic attachment of telomere to nuclear envelope grouped by MAJIN-low versus MAJIN-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAJIN→partner) and Y-score (partner→MAJIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Meiotic attachment of telomere to nuclear envelope →	-0.174	-0.762	<.001	<.001	3	25
TGCT	Telomere tethering at nuclear periphery →	-0.196	-0.879	<.001	<.001	3	25
TGCT	Chromosome attachment to the nuclear envelope →	-0.204	-0.897	<.001	<.001	3	22
ESCA	RNA 3'-end processing →	+0.080	+0.382	<.001	<.001	3	16
STAD	Positive regulation of protein ubiquitination →	+0.060	+0.318	<.001	<.001	3	15
STAD	Positive regulation of DNA metabolic process →	+0.061	+0.337	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,089 associations by consensus.

Meiotic attachment of telomere to nuclear envelope by MAJIN expression — TGCT

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