MAGT1

Across TCGA pan-cancer cohorts, MAGT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MAGT1 data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher MAGT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MAGT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

GBM, CCRCC, and HNSC are the cancer types where MAGT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.689	0.796	.004	15	view →
CCRCC	DFS	Tertile	III,IV	0.464	0.811	.010	13	view →
HNSC	DFS	Quartile	All	0.787	0.575	.041	1	view →
LUAD	OS	Median	All	0.971	0.918	.046	1	view →
PDAC	OS	Quartile	III,IV	0.575	0.885	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MAGT1–GBM (DFS)

Open the GBM breakdown →