MAGT1

Across TCGA cell cohorts, MAGT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,083 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MAGT1-associated GO terms across cancer lineages are Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Protein targeting to lysosome involved in chaperone-mediated autophagy. Each is linked with MAGT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both MAGT1-to-partner and partner-to-MAGT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway grouped by MAGT1-low versus MAGT1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGT1→partner) and Y-score (partner→MAGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.168	+0.992	<.001	<.001	3	14
BLOOD_Lymphoma	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.060	+0.863	<.001	<.001	3	14
BLOOD_Lymphoma	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.172	+0.692	<.001	<.001	3	13
BONE	Membrane protein proteolysis →	+0.104	+0.651	.003	.006	3	13
LIVER	Protein targeting to vacuole involved in autophagy →	+0.188	+0.931	<.001	.006	2	13
BREAST	Regulation of Golgi inheritance →	+0.141	+0.771	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,083 associations by consensus.

Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway by MAGT1 expression — SOFT_TISSUE

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