MAGOHB

Across TCGA pan-cancer cohorts, MAGOHB mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MAGOHB data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher MAGOHB mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MAGOHB expression acts as an unfavorable survival marker, although some lineages such as GBM and HNSC show a favorable association.

GBM and HNSC are the cancer types where MAGOHB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Quartile	All	0.602	0.118	.041	3	view →
HNSC	OS	Quartile	III,IV	0.917	0.585	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

MAGOHB–GBM (DFS)

Open the GBM breakdown →