MAGOH2P

Across TCGA pan-cancer cohorts, MAGOH2P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MAGOH2P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MAGOH2P RNA is associated with better overall survival. In most high-consensus cancer types, elevated MAGOH2P expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, BRCA, and UCS are the cancer types where MAGOH2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.453	0.291	<.001	142	view →
BRCA	DFS	Median	III,IV	0.864	0.714	.001	50	view →
UCS	DFS	Median	III,IV	0.461	0.120	<.001	50	view →
READ	OS	Tertile	II,III,IV	0.955	0.447	.011	38	view →
OV	DFS	Quartile	IV	0.515	0.255	.004	30	view →
LGG	DFS	Quartile	All	0.624	0.789	<.001	29	view →
COAD	OS	Tertile	IV	0.842	0.494	.006	25	view →
SKCM	DFS	Quartile	III,IV	0.637	0.276	<.001	23	view →
MESO	DFS	Median	IV	0.183	0.466	.020	15	view →
THYM	DFS	Median	II,III,IV	0.856	0.602	.014	15	view →
PAAD	OS	Tertile	All	0.563	0.311	.005	14	view →
LUSC	DFS	Tertile	III,IV	0.130	0.858	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MAGOH2P–HNSC (OS)

Open the HNSC breakdown →