MAGOH

Across TCGA patient cohorts, MAGOH protein abundance is significantly associated with the RNA expression of many other genes, with 2,700 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MAGOH-associated genes across cancer lineages are CRYAB, PLCB4, and CAV2. Each is linked with MAGOH in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGOH-to-partner and partner-to-MAGOH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAGOH versus CRYAB in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGOH→partner) and Y-score (partner→MAGOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CRYAB →	-1.632	-0.888	.001	.006	3	3
LSCC	PLCB4 →	-0.919	-0.422	.003	.004	3	2
BRCA	CAV2 →	-1.111	-1.084	<.001	.003	3	2
LUAD	MTFR2 →	+0.780	+0.473	<.001	<.001	3	2
LSCC	GLMN →	+0.528	+0.549	.005	.004	3	2
LSCC	FANCM →	+0.541	+0.577	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,700 associations by consensus.

MAGOH vs CRYAB — BRCA

Explore this scatter interactively →