MAGOH

Across TCGA patient cohorts, MAGOH mutation is significantly associated with the RNA expression of many other genes, with 596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGOH-associated genes across cancer lineages are SUMO2P15, RBAK-RBAKDN, and NOL12. Each is linked with MAGOH in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGOH-to-partner and partner-to-MAGOH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUMO2P15 grouped by MAGOH-low versus MAGOH-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGOH→partner) and Y-score (partner→MAGOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SUMO2P15 →	+0.310	+2.271	<.001	.003	3	1
UCEC	RBAK-RBAKDN →	+0.088	+2.227	.001	.005	3	1
UCEC	NOL12 →	+0.457	+3.475	<.001	.002	3	1
UCEC	FCGBP →	-1.159	-2.689	.005	.006	3	1
UCEC	FRG1HP →	+0.529	+2.732	.004	.003	3	1
UCEC	MIR8071-2 →	+1.029	+2.279	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

SUMO2P15 by MAGOH expression — UCEC

Explore this box plot interactively →