MAGOH

Across TCGA cell cohorts, MAGOH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,101 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAGOH-associated GO terms across cancer lineages are DNA replication initiation, CENP-A containing chromatin assembly, and Negative regulation of chromosome segregation. Each is linked with MAGOH in more than 13 cancer types. Because this analysis shows association rather than direction, both MAGOH-to-partner and partner-to-MAGOH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by MAGOH-low versus MAGOH-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGOH→partner) and Y-score (partner→MAGOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA replication initiation →	+0.141	+0.558	<.001	<.001	3	14
BREAST	CENP-A containing chromatin assembly →	+0.157	+0.825	<.001	<.001	3	13
URINARY_TRACT	Negative regulation of chromosome segregation →	+0.107	+0.558	<.001	.001	3	13
URINARY_TRACT	snoRNA guided rRNA pseudouridine synthesis →	+0.120	+0.720	<.001	<.001	3	13
SOFT_TISSUE	Protein localization to kinetochore →	+0.142	+0.619	<.001	<.001	3	13
LARGE_INTESTINE	Meiotic chromosome segregation →	+0.127	+0.559	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,101 associations by consensus.

DNA replication initiation by MAGOH expression — SOFT_TISSUE

Explore this box plot interactively →