MAGIX

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAGIX protein abundance is significantly associated with the RNA expression of many other genes, with 1,222 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MAGIX-associated genes across cancer lineages are RNA5SP473, BNIP1, and ZNF200. Each is linked with MAGIX in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGIX-to-partner and partner-to-MAGIX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAGIX versus RNA5SP473 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGIX→partner) and Y-score (partner→MAGIX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP473 →-1.026-0.519.005.00332
CCRCCBNIP1 →-0.398-0.672<.001.00232
UCECZNF200 →+0.437+0.495.001.00431
UCECCPEB3 →+0.916+0.662<.001.00931
UCECVNN1 →+1.769+0.610<.001<.00131
UCECHAVCR1 →+1.748+0.593.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,222 associations by consensus.

MAGIX vs RNA5SP473 — UCEC

Per-sample scatter of MAGIX vs RNA5SP473 in UCEC (Pearson r = -0.36).

Explore this scatter interactively →

Exploration