MAGI3

Across TCGA patient cohorts, MAGI3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,125 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MAGI3-associated proteins across cancer lineages are MAGI3_S659, LRBA, and RBM47. Each is linked with MAGI3 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAGI3-to-partner and partner-to-MAGI3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAGI3 versus MAGI3_S659 in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGI3→partner) and Y-score (partner→MAGI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MAGI3_S659 →	+1.329	+0.922	.008	.003	3	7
BRCA	LRBA →	+0.336	+0.614	<.001	<.001	3	6
BRCA	RBM47 →	+0.296	+0.824	<.001	<.001	3	5
COAD	RSBN1 →	+0.351	+0.608	<.001	<.001	3	5
UCEC	ADA →	-0.487	-0.344	<.001	.001	3	4
GBM	CALR →	-0.296	-0.472	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,125 associations by consensus.

MAGI3 vs MAGI3_S659 — BRCA

Explore this scatter interactively →