MAGI3

Across TCGA cell cohorts, MAGI3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,144 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAGI3-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Regulation of protein localization to cell cortex, and Positive regulation of Ras protein signal transduction. Each is linked with MAGI3 in more than 9 cancer types. Because this analysis shows association rather than direction, both MAGI3-to-partner and partner-to-MAGI3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by MAGI3-low versus MAGI3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGI3→partner) and Y-score (partner→MAGI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Post-Golgi vesicle-mediated transport →	+0.070	+0.875	<.001	<.001	3	10
LIVER	Regulation of protein localization to cell cortex →	+0.202	+0.820	<.001	.002	2	10
PANCREAS	Positive regulation of Ras protein signal transduction →	+0.137	+0.508	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.061	+0.980	.001	.003	3	9
LIVER	Positive regulation of protein localization to cell cortex →	+0.205	+0.706	<.001	.001	3	8
OVARY	Regulation of microtubule cytoskeleton organization →	+0.049	+0.592	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,144 associations by consensus.

Post-Golgi vesicle-mediated transport by MAGI3 expression — OVARY

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