Across TCGA patient cohorts, MAGI2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,340 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAGI2-associated genes across cancer lineages are DAAM2, CNRIP1, and LRCH2. Each is linked with MAGI2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAGI2-to-partner and partner-to-MAGI2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGI2→partner) and Y-score (partner→MAGI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DAAM2 →	+1.349	+0.403	<.001	<.001	3	5
GBM	CNRIP1 →	+0.684	+0.373	.001	<.001	3	4
PDAC	LRCH2 →	+0.771	+0.710	.001	.007	3	4
BRCA	APH1B →	+0.669	+0.565	.003	.004	3	4
PDAC	RBMS3 →	+1.055	+0.908	<.001	<.001	3	4
PDAC	FAM13C →	+0.892	+0.938	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,340 associations by consensus.

Exploration

MAGI2 survival (RNA) · tumor vs normal (RNA) · all MAGI2 data types