MAGI2-AS1

Across TCGA pan-cancer cohorts, MAGI2-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MAGI2-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MAGI2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MAGI2-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and PAAD show a favorable association.

BLCA, ESCA, and STAD are the cancer types where MAGI2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	IV	0.078	0.594	<.001	72	view →
ESCA	DFS	Tertile	III,IV	0.681	0.256	.004	28	view →
STAD	DFS	Tertile	IV	0.087	0.415	<.001	18	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
LUAD	OS	Tertile	III,IV	0.163	0.659	.035	18	view →
UCEC	DFS	Tertile	All	0.746	0.900	.017	18	view →
PAAD	OS	Tertile	All	1.000	0.294	.029	12	view →
LUSC	OS	Tertile	All	0.355	0.728	.026	9	view →
PCPG	OS	Tertile	All	0.944	1.000	.045	9	view →
LIHC	DFS	Tertile	II,III,IV	0.110	0.469	.012	9	view →
THCA	DFS	Tertile	IV	0.406	0.875	.018	6	view →
KIRP	OS	Tertile	All	0.350	0.738	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MAGI2-AS1–BLCA (OS)

Open the BLCA breakdown →